Non-steroidal anti-inflammatory drug hypersensitivity in children

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Non-steroidal anti-inflammatory drug hypersensitivity in children.

INTRODUCTION There are rather few publications about hypersensitivity reactions to non-steroidal anti-inflammatory drugs (NSAID) in the paediatric age. In this study, we aimed to assess the frequency of confirmed NSAID hypersensitivity in children with a previous reported reaction to NSAID in order to investigate the role of the drug provocation test (DPT) in the diagnostic workup and to explor...

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Non-steroidal anti-inflammatory drug-induced enteropathy

Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel injuries caused by NSAIDs, and new endoscopic techniques such as capsule endoscopy and double balloon endoscopy can help in detecting such inj...

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Hypersensitivity to non-steroidal anti-inflammatory drugs in pediatric patients

Results Medical records of 104 individuals with a history of hypersensitivity to drugs were analyzed. NSAIDs were the primarily suspected drug in 50% of the cases. The mean age was 10.9 years, with a predominance of males (57.7%). All patients had cutaneous manifestations and isolated angioedema was observed in the majority (53.8%); respiratory symptoms were reported in 44% of cases and gastroi...

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375 Non-steroidal Anti-inflammatory Drugs Hypersensitivity: Patterns of Reaction

FL; Division of Allergy & Immunology, University of South. Background: The U.S.A. Accreditation Council for Graduate Medical Education (ACGME) requires that graduate medical education programs in A/I prepare specialists to provide expert medical care for patients with A/I disorders. The A/I intensive education course (boot camp) program was implemented at the University of South Florida (USF) t...

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Protective Effect of H pylori Infection in Non-Steroidal Anti-Inflammatory Drug Users

Background: Non-steroidal anti-inflammatory drug (NSAID) use and H pylori infection are two major causes of peptic ulcers. This study investigates the effect of H pylori infection and NSAIDs on gastroduodenal damages and bleeding (GIB). Methods: 104 patients with acute gastrointestinal bleeding (GIB) and 102 patients with dyspepsia without bleeding were studied. Duodenal (DU) and gastric ulcers...

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ژورنال

عنوان ژورنال: Allergologia et Immunopathologia

سال: 2017

ISSN: 0301-0546

DOI: 10.1016/j.aller.2016.04.004